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  1. Immunotherapy for Hepatocellular Carcinoma

    Background: Hepatocellular carcinoma (HCC), the most common primary malignancy of the liver, is the fifth most common cancer in men and seventh among...
    Living reference work entry 2023
  2. Liquid Biopsy in Hepatocellular Carcinoma

    Hepatocellular carcinoma (HCC) is one of the most deadly neoplasms with a poor prognosis. Due to the significant tumor heterogeneity of HCC,...
    Zheyu Zhou, **aoliang Xu, ... Yin Yin in Liquid Biopsies
    Protocol 2023
  3. Orthotopic Model of Hepatocellular Carcinoma in Mice

    Orthotopic models of hepatocellular carcinoma (HCC) consist in the implantation of tumor cells into the liver by direct intrahepatic injection. In...
    Flavia Lambertucci, Si**g Li, ... Isabelle Martins in Liver Carcinogenesis
    Protocol 2024
  4. DEN-Induced Hepatocellular Carcinoma in Animal Model

    Cancer is a major cause of death both in developed and develo** countries. Among the various types of cancers, primary liver cancer represents...
    K. Sivakumari, P. Janani, S. Rajesh in Handbook of Animal Models and its Uses in Cancer Research
    Reference work entry 2023
  5. Synbiotics in Hepatocellular Carcinoma

    Cancer is a deadly disease that affect a wide range of population worldwide. It is accounting for nearly 10 million deaths in 2020, or nearly one in...
    Kuttiappan Anitha, Jamal Basha Dudekula, ... Shvetank Bhatt in Synbiotics for the Management of Cancer
    Chapter 2023
  6. Hepatocellular carcinoma immune prognosis score predicts the clinical outcomes of hepatocellular carcinoma patients receiving immune checkpoint inhibitors

    Objective

    The predictive biomarkers of immune checkpoint inhibitors (ICIs) in hepatocellular carcinoma (HCC) still need to be further explored. This...

    Rujia Zhang, Haoran Zhao, ... Zhaowei Qu in BMC Cancer
    Article Open access 01 December 2023
  7. Drug Resistance in Hepatocellular Carcinoma

    At present, the burden of cancer morbidity and mortality is increasing all over the world. Among all kinds of cancer, primary liver cancer is...
    **nxin Chen, ** Li, ... Chao Liang in Hepatobiliary Cancers: An Interdisciplinary Approach
    Chapter 2023
  8. Fibrosis and Immunotherapy in Hepatocellular Carcinoma

    Hepatocellular carcinoma (HCC) is difficult-to-treat cancer, despite great advances in systemic therapy, with a median survival of 6ā€“20 months, due...
    Sarah B. White, Dilip Rajasekhar Maddirela in Hepatobiliary Cancers: An Interdisciplinary Approach
    Chapter 2023
  9. Interferon-induced transmembrane protein 3 in hepatocellular carcinoma patients

    Objective

    The study aimed to investigate the over expression of IFITM3 in hepatocellular carcinoma Egyptian patients.

    Background

    Hepatocellular...

    Rania M. Bondok, Lamiaa A. Barakat, ... Maivel H. Ghattas in BMC Cancer
    Article Open access 23 June 2023
  10. Spatially resolved visualization of reprogrammed metabolism in hepatocellular carcinoma by mass spectrometry imaging

    Background

    Metabolic reprogramming refers to tumor-associated metabolic alterations during tumorigenesis and has been regarded as one of the most...

    Bangzhen Ma, Yang Zhang, ... Chengkun Qin in Cancer Cell International
    Article Open access 24 August 2023
  11. Orientin regulates the proliferation and migration of hepatocellular carcinoma cells

    Orientin is a flavone isolated from medicinal plants used in traditional Chinese medicine (TCM) that suppresses the growth of cancer cells in vitro....

    Jia-Yi Tao, **g Li, ... Li-Peng Wan in Naunyn-Schmiedeberg's Archives of Pharmacology
    Article 13 May 2023
  12. Hub gene identification and immune infiltration analysis in hepatocellular carcinoma: Computational approach

    In the case of hepatocellular carcinoma, there is a need to find novel immune biomarkers to predict cancer prognosis, which will help prolong patient...

    Swetha Pulakuntla, Shri Abhiav Singh, Vaddi Damodara Reddy in In Silico Pharmacology
    Article 06 May 2024
  13. Hsa_circ_0005397 promotes hepatocellular carcinoma progression through EIF4A3

    Purpose

    The purpose of this study was to explore the expression and potential mechanism of hsa_circ_0005397 in hepatocellular carcinoma progression.

    ...
    Liu-**a Yuan, Mei Luo, ... Lin Chen in BMC Cancer
    Article Open access 21 February 2024
  14. DEN-Induced Hepatocellular Carcinoma in Animal Model

    Cancer is a major cause of death both in developed and develo** countries. Among the various types of cancers, primary liver cancer represents...
    K. Sivakumari, P. Janani, S. Rajesh in Handbook of Animal Models and its Uses in Cancer Research
    Living reference work entry 2022
  15. A Mouse Model of Hepatocellular Carcinoma Induced by Streptozotocin and High-Fat Diet

    Hepatocellular carcinoma (HCC) is the most common type of liver cancer and the second most common cause of cancer-related death. HCC is associated to...
    Omar MotiƱo, Si**g Li, ... Isabelle Martins in Liver Carcinogenesis
    Protocol 2024
  16. Perspectives in Biochemical Staging of Hepatocellular Carcinoma Over the Current Microscopical Methodology

    Hepatocellular carcinoma (HCC) is considered the third main cause of cancer-related deaths globally. Comparing with other tumors, survival of HCC...
    Nabil Mohie Abdel-Hamid, Shimaa Ali Abass in Handbook of Cancer and Immunology
    Living reference work entry 2023
  17. Heterogeneity of hepatocellular carcinoma: from mechanisms to clinical implications

    Hepatocellular Carcinoma (HCC) is one of the most common types of primary liver cancer. Current treatment options have limited efficacy against this...

    Fatema Safri, Romario Nguyen, ... Liang Qiao in Cancer Gene Therapy
    Article Open access 18 March 2024
  18. An overview of mouse models of hepatocellular carcinoma

    Hepatocellular carcinoma (HCC) has become a severe burden on global health due to its high morbidity and mortality rates. However, effective...

    Hua-chuan Zheng, Hang Xue, Wen-**g Yun in Infectious Agents and Cancer
    Article Open access 05 September 2023
  19. Deep dissection of stemness-related hierarchies in hepatocellular carcinoma

    Background

    Increasing evidence suggests that hepatocellular carcinoma (HCC) stem cells (LCSCs) play an essential part in HCC recurrence, metastasis,...

    Rui Liang, Weifeng Hong, ... Guanbin Song in Journal of Translational Medicine
    Article Open access 16 September 2023
  20. G6PD and machine learning algorithms as prognostic and diagnostic indicators of liver hepatocellular carcinoma

    Background

    Liver Hepatocellular carcinoma (LIHC) exhibits a high incidence of liver cancer with escalating mortality rates over time. Despite this,...

    Fei Li, Boshen Wang, ... Baoli Zhu in BMC Cancer
    Article Open access 31 January 2024